Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104319 | 0.86 | TTK (0.71) | TTK | |
| SCHEMBL135284 | 0.84 | TTK (0.74) | TTK | |
| SCHEMBL178466 | 0.83 | TTK (0.77) | TTK | |
| SCHEMBL105407 | 0.81 | TTK (0.72) | TTK | |
| SCHEMBL135281 | 0.80 | TTK (0.88) | TTK | |
| SCHEMBL178566 | 0.80 | TTK (0.71) | TTK | |
| SCHEMBL136242 | 0.80 | TTK (0.74) | TTK | |
| SCHEMBL178456 | 0.80 | TTK (0.77) | TTK | |
| SCHEMBL105105 | 0.80 | TTK (0.77) | TTK | |
| SCHEMBL456437 | 0.80 | TTK (0.77) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460805-A1 | FUSED IMIDAZOLE DERIVATIVE HAVING TTK INHIBITORY ACTION | Oncotherapy Science, Inc. (JP) | 2012-06-06 | — | — | EP | disclosed |