⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983124 | 1.00 | — | — | |
| SCHEMBL1983123 | 1.00 | — | — | |
| SCHEMBL2214726 | 1.00 | — | — | |
| SCHEMBL9073808 | 0.84 | — | — | |
| SCHEMBL6444658 | 0.75 | — | — | |
| SCHEMBL3782729 | 0.75 | — | — | |
| SCHEMBL9069796 | 0.75 | — | — | |
| SCHEMBL519001 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL15539545 | 0.73 | — | — | |
| SCHEMBL1676805 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924275-B1 | THIO-CONTAINING INHIBITORS OF AMINOPEPTIDASE P, COMPOSITIONS THEREOF AND METHOD OF USE | SIMMONS WILLIAM H (US) | 2012-08-08 | — | — | EP | claimed |
| US-20070060525-A1 | Thio-containing inhibitors of aminopeptidase P, compositions thereof and method of use | SIMMONS WILLIAM H | 2007-03-15 | — | — | US | claimed |
| EP-0708085-A2 | Antiviral ethers of aspartate protease substrate isosteres | CIBA-GEIGY AG (CH) | 1996-04-24 | — | — | EP | claimed |
| US-4503040-A | 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors | PFIZER INC. (US) | 1985-03-05 | — | — | US | claimed |
| WO-2023071895-A1 | HYDROXYPROLYL-SERINE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州裕泰医药科技有限公司 | 2023-05-04 | — | — | WO | disclosed |
| WO-2023071896-A1 | HYDROXYPROLYL-SERINE COMPOUND, AND PREPARATION AND APPLICATION THEREOF | 苏州裕泰医药科技有限公司 | 2023-05-04 | — | — | WO | disclosed |
| US-20230022724-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-01-26 | — | — | US | disclosed |
| EP-3897840-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. Hoffmann-La Roche AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| CN-113164771-A | Imidazopyrazine derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020126956-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2014041560-A2 | PROCESS FOR THE PREPARATION OF TENELIGLIPTIN | GLENMARK PHARMACEUTICALS LIMITED; GLENMARK GENERICS LIMITED (IN) | 2014-03-20 | — | — | WO | disclosed |
| EP-1924275-B1 | THIO-CONTAINING INHIBITORS OF AMINOPEPTIDASE P, COMPOSITIONS THEREOF AND METHOD OF USE | SIMMONS WILLIAM H (US) | 2012-08-08 | — | — | EP | disclosed |
| US-5663200-A | CARBAMOYL PEPTIDE DERIVATIVES AS VIRICIDES | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0790254-A1 | Pseudopeptides derived from neurokinines, process of preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1997-08-20 | — | — | EP | disclosed |
| US-5561113-A | ANALGESICS; ANTIIFLAMMATORY AGENTS; GASTROINTESTINAL, UROGENITAL AND NERVOUS SYSTEM(CNS) DISORDERS; ASTHMA; ANTIALLERGENS | ADIR ET COMPAGNIE (FR) | 1996-10-01 | — | — | US | disclosed |
| WO-1996016980-A1 | MORPHOLINOETHYLAMIDE DERIVATIVES | NOVARTIS AG (CH) | 1996-06-06 | — | — | WO | disclosed |
| EP-0708085-A2 | Antiviral ethers of aspartate protease substrate isosteres | CIBA-GEIGY AG (CH) | 1996-04-24 | — | — | EP | disclosed |
| CN-1120548-A | New pseudopeptide compounds of neurokinins, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1996-04-17 | — | — | CN | disclosed |
| EP-0594540-A1 | Antiretroviral acyl compounds | CIBA-GEIGY AG (CH) | 1994-04-27 | — | — | EP | disclosed |
| US-4591459-A | Intermediates for 6-(aminoacyloxymethyl) penicillanic acid 1,1-dioxides | PFIZER INC. (US) | 1986-05-27 | — | — | US | disclosed |