SCHEMBL10283902

SCHEMBL10283902

Cc1ccc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc1CF

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SSTR5 P35346 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14957252 0.84 SSTR5 (0.71) SSTR5
SCHEMBL14969664 0.83 SSTR5 (0.66) SSTR5
SCHEMBL14969652 0.82 SSTR5 (0.68) SSTR5
SCHEMBL671089 0.82 SSTR5 (1.00) SSTR5
SCHEMBL15756164 0.82 SSTR5 (0.66) SSTR5
SCHEMBL672565 0.82 SSTR5 (0.73) SSTR5
SCHEMBL14969621 0.82 SSTR5 (0.62) SSTR5
SCHEMBL14969653 0.82 SSTR5 (0.69) SSTR5
SCHEMBL17612761 0.82 SSTR5 (0.63) SSTR5
SCHEMBL14969631 0.81 SSTR5 (0.69) SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012024183-A1 SPIROXAZOLIDINONE COMPOUNDS MERCK SHARP & DOHME CORP. (US) 2012-02-23 — — WO disclosed
Send feedback