SCHEMBL102853

SCHEMBL102853

C=Cc1ccc(OCOc2ccc(OC(=O)c3ccc(C=C)cc3)cc2C)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
KMT2A Q03164 9/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 5/20 0.38
GFER P55789 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 2/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
PPARD Q03181 2/20 0.36
HPGD P15428 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
NPC1 O15118 1/20 0.36
NR1H4 Q96RI1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13774490 0.93 KMT2A (0.42) TDP1L3MBTL1KMT2ALMNAMAPT
SCHEMBL14192477 0.88 TDP1 (0.39) TDP1L3MBTL1KMT2ALMNAMAPT
SCHEMBL16812834 0.87 KDM4E (0.44) KMT2ALMNAMAPTGFERKDM4E
SCHEMBL103708 0.86 AKR1C3 (0.41) TDP1L3MBTL1KMT2ALMNAMAPT
SCHEMBL14590324 0.86 KMT2A (0.51) TDP1L3MBTL1KMT2ALMNAMAPT
SCHEMBL5961817 0.86 KMT2A (0.39) TDP1L3MBTL1KMT2ALMNAMAPT
SCHEMBL14524371 0.86 NPC1 (0.34) TDP1L3MBTL1KMT2ALMNAMAPT
SCHEMBL15711684 0.86 MAPT (0.36) TDP1L3MBTL1KMT2ALMNAMAPT
SCHEMBL103307 0.85 HPGD (0.36) TDP1KMT2AMAPTGFERKDM4E
SCHEMBL13390123 0.85 NPC1 (0.38) TDP1L3MBTL1KMT2AMAPTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-9828548-B2 Liquid-crystal composition DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9809752-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-20170283699-A1 REACTIVE MESOGEN FORMULATION WITH CONDUCTIVE ADDITIVE MERCK PATENT GMBH (DE) 2017-10-05 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160130502-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-05-12 US disclosed
US-20150259600-A1 LIQUID-CRYSTAL COMPOSITION DIC CORPORATION (JP) 2015-09-17 US disclosed
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-20140327862-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITION AND FERROELECTRIC LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2014-11-06 US disclosed
US-20140313468-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2014-10-23 US disclosed
US-7514126-B2 Optical element obtained by homeotropically orienting liquid crystal molecule, member for liquid crystal display device using the same, and liquid crystal display device DAI NIPPON PRINTING CO., LTD. (JP) 2009-04-07 US disclosed
US-20090059136-A1 COMPOSITE POLARIZING PLATE WITH WIDE FIELD OF VIEW AND LIQUID CRYSTAL DISPLAY SUMITOMOCHEMICAL COMPANY, LIMITED (JP) 2009-03-05 US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 US disclosed
US-20090040433-A1 LIQUID CRYSTAL DISPLAY DEVICE AND COLOR FILM PLATE, AND PROCESSES FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2009-02-12 US disclosed
US-20090033834-A1 LIQUID CRYSTAL LAYER FORMING INK COMPOSITION, AND OPTICAL FILM, POLARIZING FILM AND LIQUID CRYSTAL DISPLAY PRODUCED WITH THE INK COMPOSITION DAI NIPPON PRINTING CO., LTD. (JP) 2009-02-05 US disclosed
US-20080180608-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICAL DEVICE, METHOD OF MANUFACTURING OPTICAL DEVICE, AND LIQUID CRYSTAL DISPLAY SONY CORPORATION (JP) 2008-07-31 US disclosed
US-7379141-B2 Color filter comprising retardation control layer, method for manufacturing the same, and display DAI NIPPON PRINTING CO., LTD. (JP) 2008-05-27 US disclosed
US-7342623-B2 Optical element and liquid crystal display device using the same DAI NIPPON PRINTING CO., LTD. (JP) 2008-03-11 US disclosed
US-7286199-B2 Phase difference control component having columnar material DAI NIPPON PRINTING CO., LTD. (JP) 2007-10-23 US disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 TDP1 2696/4885L3MBTL1 236/4885KMT2A 1510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.