Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800222 | 0.86 | KDM4E (0.45) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL2800681 | 0.85 | BLM (0.43) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL2799928 | 0.84 | HPGD (0.41) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL2799947 | 0.84 | HPGD (0.51) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL2799478 | 0.84 | HPGD (0.51) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL10285856 | 0.84 | HPGD (0.41) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL12002176 | 0.84 | HPGD (0.41) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL2796878 | 0.82 | KDM4E (0.59) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL2795089 | 0.82 | HPGD (0.40) | ALDH1A1HPGDLMNAMAPTNPC1 | |
| SCHEMBL2797971 | 0.82 | BLM (0.53) | ALDH1A1HPGDLMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |