Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287937 | 0.92 | ABL1 (0.81) | ABL1 | |
| SCHEMBL10287729 | 0.90 | ABL1 (1.00) | ABL1 | |
| SCHEMBL10288286 | 0.90 | ABL1 (0.85) | ABL1 | |
| SCHEMBL10287717 | 0.88 | ABL1 (0.81) | ABL1 | |
| SCHEMBL14297832 | 0.88 | ABL1 (0.85) | ABL1 | |
| SCHEMBL9939547 | 0.86 | ABL1 (0.82) | ABL1 | |
| SCHEMBL18899748 | 0.86 | ABL1 (0.79) | ABL1 | |
| SCHEMBL14297759 | 0.86 | ABL1 (1.00) | ABL1 | |
| SCHEMBL10287763 | 0.85 | ABL1 (0.66) | ABL1 | |
| SCHEMBL9939366 | 0.85 | ABL1 (0.85) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080284-A2 | SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2012-06-21 | — | — | WO | disclosed |