SCHEMBL1029072

SCHEMBL1029072

C=Cc1ccccc1OCc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.62
CDK1 P06493 1/20 0.62
CDK4 P11802 1/20 0.62
CCNB1 P14635 1/20 0.62
CCND1 P24385 1/20 0.62
CCNB3 Q8WWL7 1/20 0.62
PTGER1 P34995 1/20 0.55
PTGER4 P35408 1/20 0.55
PTGER3 P43115 1/20 0.55
PTGER2 P43116 1/20 0.55
MAPT P10636 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPK1 P28482 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
NPC1 O15118 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8344663 0.87 MAPT (0.51) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL8344558 0.87 MAOB (0.50) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL6885148 0.87 MAPT (0.50) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL28374924 0.86 CCNB2 (0.47) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL34465996 0.84 CCNB2 (0.50) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL27722639 0.84 CDK4 (0.71) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL20767538 0.83 CCNB2 (0.49) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL12804678 0.83 CCNB2 (0.49) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL29241974 0.83 CYP11B1 (0.46) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL6428087 0.82 CYP1A2 (0.58) MAPTL3MBTL1KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155729-B2 Graft copolymers and compositions thereof CLARIANT INTERNATIONAL LTD. (CH) 2021-10-26 US claimed
CN-108431140-B Graft copolymer and composition thereof 科莱恩国际有限公司 2021-07-02 CN claimed
US-20190153257-A1 GRAFT COPOLYMERS AND COMPOSITIONS THEREOF CLARIANT INTERNATIONAL LTD. (CH) 2019-05-23 US claimed
EP-3458526-A1 GRAFT COPOLYMERS AND COMPOSITIONS THEREOF Clariant International Ltd (CH) 2019-03-27 EP claimed
WO-2017198428-A1 GRAFT COPOLYMERS AND COMPOSITIONS THEREOF CLARIANT INTERNATIONAL LTD (CH) 2017-11-23 WO claimed
EP-3246365-A1 GRAFT COPOLYMERS AND COMPOSITIONS THEREOF Clariant International Ltd (CH) 2017-11-22 EP claimed
EP-1853327-B1 MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH COPOLYMERS CONTAINING HYDROCARBON AND HETEROATOM-CONTAINING MONOMERIC SPECIES BOSTON SCIENT LTD (BB) 2012-11-07 EP claimed
EP-1853327-A2 MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH COPOLYMERS CONTAINING HYDROCARBON AND HETEROATOM-CONTAINING MONOMERIC SPECIES Boston Scientific Limited (BB) 2007-11-14 EP claimed
WO-2006083628-A2 MEDICAL DEVICES HAVING POLYMERIC REGIONS WITH COPOLYMERS CONTAINING HYDROCARBON AND HETEROATOM-CONTAINING MONOMERIC SPECIES BOSTON SCIENTIFIC SCIMED, INC. (US) 2006-08-10 WO claimed
US-20060171981-A1 Medical devices having polymeric regions with copolymers containing hydrocarbon and heteroatom-containing monomeric species BOSTON SCIENTIFIC SCIMED, INC. 2006-08-03 US claimed
EP-4720076-A1 SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS H. Lundbeck A/S (DK) 2026-04-08 EP disclosed
US-12590106-B2 Spiromacrocyclic orexin 2 receptor agonists H. LUNDBECK A/S (DK) 2026-03-31 US disclosed
US-20250263422-A1 SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS H. LUNDBECK A/S (DK) 2025-08-21 US disclosed
CN-115244093-B Acrylate rubber, acrylate rubber-containing composition, and rubber crosslinked product 株式会社大阪曹达 2025-05-23 CN disclosed
CN-114040931-B Copolymer latex for adhesive and adhesive composition 日本A&L株式会社 2025-02-11 CN disclosed
EP-0520626-A1 Radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-12-30 EP disclosed
EP-0333758-A4 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. COMMW SCIENT IND RES ORG (AU) 1990-05-14 EP disclosed
EP-0333758-A1 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. COMMW SCIENT IND RES ORG (AU) 1989-09-27 EP disclosed
US-4791176-A Alkenylphenol and alkenylphenol ether copolymers SIEMENS AKTIENGESELLSCHAFT (DE) 1988-12-13 US disclosed
WO-1988004304-A1 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1988-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590106-B2 Spiromacrocyclic orexin 2 receptor agonists HCRTR2, HCRTR1, OXER1 CCNB2 2599/4885CDK1 2255/4885CDK4 4385/4885
US-20250263422-A1 SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS HCRTR2, HCRTR1, CRHR2 CCNB2 2214/4885CDK1 2525/4885CDK4 3596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.