Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029496 | 1.00 | CNR1 (0.48) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL1028799 | 0.85 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL5318133 | 0.82 | CNR1 (0.56) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL5318134 | 0.82 | CNR1 (0.56) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL1029218 | 0.80 | CNR1 (0.51) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL1029217 | 0.80 | CNR1 (0.51) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL1030628 | 0.79 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL1030626 | 0.79 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL1029770 | 0.77 | CNR1 (0.54) | CNR1CNR2 | |
| SCHEMBL1029771 | 0.77 | CNR1 (0.54) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1804791-B1 | TETRAHYDRO PYRIDINYL PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-01-19 | — | — | EP | disclosed |