Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.78 |
| ▸ | PDE4A | P27815 | 11/20 | 0.78 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.78 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029620 | 1.00 | PDE4B (0.78) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1030400 | 0.99 | PDE4B (0.77) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1030398 | 0.99 | PDE4B (0.77) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1030952 | 0.92 | PDE4B (0.90) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1030951 | 0.92 | PDE4B (0.90) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1032135 | 0.92 | PDE4B (0.90) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1032134 | 0.92 | PDE4B (0.90) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1029821 | 0.88 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL1029820 | 0.88 | PDE4B (1.00) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL4885939 | 0.83 | PDE4D (0.61) | PDE4BPDE4DPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044023-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDYNYL ALKYLENE ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMA SPA (IT) | 2011-01-19 | — | — | EP | disclosed |