SCHEMBL10296350

SCHEMBL10296350

N#C/C(=C1C(=C(\C#N)c2c(F)c(F)c(C(F)(F)F)c(F)c2F)C/1=C(\C#N)c1c(F)c(F)c(F)c(F)c1F)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25679056 1.00 TSHR (0.31) TSHRSMN1; SMN2
SCHEMBL27104609 0.98 TSHR (0.30) TSHRSMN1; SMN2
SCHEMBL1323658 0.98 TSHR (0.32) TSHRSMN1; SMN2
SCHEMBL14903567 0.92 — —
SCHEMBL25679075 0.92 — —
SCHEMBL10296278 0.91 AR (0.33) —
SCHEMBL23164564 0.90 TSHR (0.30) TSHRSMN1; SMN2
SCHEMBL13063414 0.90 — —
SCHEMBL23161868 0.89 — —
SCHEMBL25251547 0.89 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024043018-A1 ORGANIC EL ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE 東レ株式会社 2024-02-29 — — WO disclosed
US-9028979-B2 Phenanthroazole compounds as hole transporting materials for electro luminescent devices BASF SE (DE) 2015-05-12 — — US disclosed
US-20120168731-A1 PHENANTHROAZOLE COMPOUNDS AS HOLE TRANSPORTING MATERIALS FOR ELECTRO LUMINESCENT DEVICES BASF SE (DE) 2012-07-05 — — US disclosed
US-20110315967-A1 Organic field effect transistor with improved current on/off ratio and controllable threshold shift BASF SE (DE) 2011-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120168731-A1 PHENANTHROAZOLE COMPOUNDS AS HOLE TRANSPORTING MATERIALS FOR ELECTRO LUMINESCENT DEVICES SLCO1B3, SLCO4C1, SLCO1B1 TSHR 4024/4885SMN1; SMN2 4267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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