SCHEMBL1029652

SCHEMBL1029652

CCOC(=O)N1CC(=Cc2ccc(OC)cc2)c2c(c(C(=O)NC(C)c3ccccc3)nn2-c2ccc(Cl)cc2Cl)C1

nearest known ligand 0.83

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 20/20 0.83
CNR2 P34972 15/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1029649 1.00 CNR1 (0.83) CNR1CNR2
SCHEMBL1029650 1.00 CNR1 (0.83) CNR1CNR2
SCHEMBL1029647 1.00 CNR1 (0.83) CNR1CNR2
SCHEMBL12956144 0.94 CNR1 (0.85) CNR1CNR2
SCHEMBL1027456 0.92 CNR1 (0.85) CNR1CNR2
SCHEMBL1031523 0.91 CNR1 (0.80) CNR1CNR2
SCHEMBL1025554 0.91 CNR1 (0.80) CNR1CNR2
SCHEMBL1025555 0.91 CNR1 (0.80) CNR1CNR2
SCHEMBL1025556 0.91 CNR1 (0.80) CNR1CNR2
SCHEMBL1026744 0.91 CNR1 (0.74) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1804791-B1 TETRAHYDRO PYRIDINYL PYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-01-19 EP claimed
EP-1804791-B1 TETRAHYDRO PYRIDINYL PYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-01-19 EP disclosed