Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13678804 | 1.00 | F10 (0.77) | F10 | |
| SCHEMBL1029716 | 0.93 | F10 (0.71) | F10 | |
| SCHEMBL13678827 | 0.93 | F10 (0.71) | F10 | |
| SCHEMBL1030621 | 0.91 | F10 (0.78) | F10 | |
| SCHEMBL8262068 | 0.90 | F10 (0.77) | F10 | |
| SCHEMBL1028708 | 0.89 | F10 (0.75) | F10 | |
| SCHEMBL13678828 | 0.89 | F10 (0.75) | F10 | |
| SCHEMBL8261774 | 0.89 | F10 (0.84) | F10 | |
| SCHEMBL1030154 | 0.89 | F10 (0.84) | F10 | |
| SCHEMBL12955865 | 0.88 | F10 (0.73) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814855-B1 | DICARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-01-19 | — | — | EP | disclosed |
| EP-1814855-A2 | DICARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006048152-A2 | DICARBOXAMIDE DERIVATIVES AND THEIR USE AS FACTOR XA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-05-11 | — | — | WO | disclosed |