Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.47 |
| ▸ | RAB9A | P51151 | 14/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | MECP2 | P51608 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651756 | 0.94 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL10299032 | 0.92 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL17614166 | 0.92 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL21312049 | 0.92 | KDM4E (0.48) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL12680697 | 0.91 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL15371751 | 0.91 | KDM4E (0.47) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL11998253 | 0.91 | KDM4E (0.47) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL18119277 | 0.91 | KDM4E (0.44) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL17125591 | 0.90 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2TSHRHPGD | |
| SCHEMBL11998177 | 0.90 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133177-B2 | Ambipolar small molecule hosts for phosphorescent guest emitters | GEORGIA TECH RESEARCH CORPORATION (US) | 2015-09-15 | — | — | US | disclosed |
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172556-A1 | POLYMERIZABLE AMBIPOLAR HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD1, OCIAD2, OXA1L | NPC1 643/4885RAB9A 2633/4885SMN1; SMN2 4701/4885 |
| US-20120168732-A1 | AMBIPOLAR SMALL MOLECULE HOSTS FOR PHOSPHORESCENT GUEST EMITTERS | OCIAD2, OCIAD1, ORC3 | NPC1 816/4885RAB9A 1811/4885SMN1; SMN2 4781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.