Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2060059 | 0.89 | TLR7 (0.53) | TLR7 | |
| SCHEMBL2060539 | 0.79 | TLR7 (0.52) | TLR7 | |
| SCHEMBL2060216 | 0.79 | TMIGD3 (0.55) | TLR7 | |
| SCHEMBL5471545 | 0.79 | TLR7 (0.53) | TLR7 | |
| SCHEMBL12900274 | 0.77 | HDAC1 (0.49) | TLR7HDAC1HDAC2 | |
| SCHEMBL2060135 | 0.77 | TLR7 (0.71) | TLR7 | |
| SCHEMBL5459700 | 0.76 | TLR7 (0.54) | TLR7 | |
| SCHEMBL5471380 | 0.76 | TLR7 (0.49) | TLR7 | |
| SCHEMBL5459709 | 0.76 | TLR7 (0.75) | TLR7 | |
| SCHEMBL5468674 | 0.76 | TLR7 (0.67) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1550662-B1 | ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO (JP) | 2012-07-04 | — | — | EP | disclosed |