⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3991269 | 1.00 | — | — | |
| SCHEMBL3989867 | 1.00 | — | — | |
| SCHEMBL9755608 | 0.72 | FFAR3 (0.30) | — | |
| SCHEMBL5030208 | 0.69 | — | — | |
| SCHEMBL5320519 | 0.69 | — | — | |
| SCHEMBL4413029 | 0.69 | — | — | |
| SCHEMBL7754675 | 0.67 | — | — | |
| SCHEMBL6337686 | 0.67 | — | — | |
| SCHEMBL19415804 | 0.67 | TSHR (0.32) | — | |
| SCHEMBL17874833 | 0.67 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699986-A | AZETIDINE INTERMEDIATES FOR ISOCEPHALOSPORINS | HOFMANN-LA ROCHE INC. (US) | 1987-10-13 | — | — | US | claimed |
| EP-0156976-B1 | OPTICALLY UNIFORM IMINES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-09-30 | — | — | EP | claimed |
| EP-0156976-A2 | Optically uniform imines | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-10-09 | — | — | EP | claimed |
| US-3962338-A | Novel methods and compounds employed therein | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | claimed |
| JP-61233693-A | — | — | None | — | — | JP | disclosed |
| JP-5238999-A | — | — | None | — | — | JP | disclosed |
| EP-3071563-B1 | ANTI-CANCER AGENTS AND PREPARATION THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2023-04-19 | — | — | EP | disclosed |
| CN-113773333-A | Anticancer agent and preparation thereof | 普渡研究基金会 | 2021-12-10 | — | — | CN | disclosed |
| CN-113461705-A | Anticancer agent and preparation thereof | 普渡研究基金会 | 2021-10-01 | — | — | CN | disclosed |
| CN-108912055-B | Method for synthesizing antiviral drug cidofovir intermediate and bucyclovir intermediate | 河南师范大学 | 2020-06-30 | — | — | CN | disclosed |
| US-10000505-B2 | Anti-cancer agents and preparation thereof | PURDUE RESEARCH FOUNDATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-9790252-B2 | 2-fluorinated riboses and arabinoses and methods of use and synthesis | CORNELL UNIVERSITY (US) | 2017-10-17 | — | — | US | disclosed |
| EP-0096297-A2 | Process for the preparation of 1-sulfo-2-oxoazetidine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-12-21 | — | — | EP | disclosed |
| EP-0096296-A2 | 1-Sulfo-2-oxoazetidine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-12-21 | — | — | EP | disclosed |
| EP-0073061-A2 | Optically uniform beta-lactams, their preparation and use in the preparation of antimicrobial beta-lactams, and starting compounds for use in their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-03-02 | — | — | EP | disclosed |
| US-4312859-A | ANTIBIOTICS, BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
| EP-0009075-A1 | Pyridyloxy-propanol amines and esters thereof, process for preparing the same and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1980-04-02 | — | — | EP | disclosed |
| US-4097490-A | Pyroglutamic acid salts of t-butylamino-2,3-dihydroxypropane | MERCK & CO., INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4031125-A | 3-Sulfonate ester of 2,3-dihydroxypropylamine | MERCK & CO., INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-3962338-A | Novel methods and compounds employed therein | MERCK & CO., INC. (US) | 1976-06-08 | — | — | US | disclosed |