Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3171431 | 0.87 | POLB (0.51) | POLBMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4840473 | 0.85 | SMN1; SMN2 (0.51) | POLBSMN1; SMN2KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4840463 | 0.83 | SMN1; SMN2 (0.50) | POLBSMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL2056407 | 0.82 | POLB (0.65) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6249295 | 0.82 | POLB (0.49) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13948407 | 0.82 | MAPT (0.57) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5184390 | 0.82 | SMN1; SMN2 (0.55) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL31601639 | 0.82 | SMN1; SMN2 (0.55) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4824629 | 0.81 | SMN1; SMN2 (0.54) | POLBSMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL4247879 | 0.81 | SMN1; SMN2 (0.54) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1550662-B1 | ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO (JP) | 2012-07-04 | — | — | EP | disclosed |