⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18714771 | 0.79 | — | — | |
| SCHEMBL13559807 | 0.78 | — | — | |
| SCHEMBL18487367 | 0.75 | — | — | |
| SCHEMBL5268956 | 0.72 | — | — | |
| SCHEMBL22781257 | 0.71 | — | — | |
| SCHEMBL5210963 | 0.71 | — | — | |
| SCHEMBL7865959 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL15027010 | 0.69 | — | — | |
| SCHEMBL20281973 | 0.69 | TSHR (0.37) | — | |
| SCHEMBL22222099 | 0.69 | GRM4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092086-A1 | COMPOSITIONS AND METHODS FOR REGENERATING CORNEAL ENDOTHELIUM | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-05-02 | — | — | WO | disclosed |
| US-20230150921-A1 | PHENOLIC ACID LIPID BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2023-05-18 | — | — | US | disclosed |
| EP-3357931-B1 | METHODS OF SYNTHESIS OF TRITERPENE PROSAPOGENINS AND TRITERPENE SAPONINS | SLOAN KETTERING INST CANCER RES (US) | 2020-07-22 | — | — | EP | disclosed |
| US-20120172411-A1 | NOVEL TRIALKYL CATIONIC LIPIDS AND METHODS OF USE THEREOF | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2012-07-05 | — | — | US | disclosed |