Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200754 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL101278 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL102975 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL25177168 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL10582094 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL25171019 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL100176 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL25173992 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL201237 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL101987 | 1.00 | TSHR (0.52) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655264-B2 | Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil | APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) | 2023-05-23 | — | — | US | claimed |
| CN-108559012-A | Synthetic lubricant base oil metallocene poly-alpha olefins catalyst and its preparation and application | 亚培烯科技（杭州）有限公司 | 2018-09-21 | — | — | CN | claimed |
| US-20180258112-A1 | Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil | APALENE TECHNOLOGY CO., LTD. (JIAXING) (CN) | 2018-09-13 | — | — | US | claimed |
| CN-106146692-A | Synthetic lubricant base oil metallocene poly-alpha olefins catalyst and its preparation method and application | 苏州亚培克生物科技有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-106046211-A | Metallocene poly-alpha olefin catalyst for synthesizing lubricating oil base oil and preparation method and application thereof | 苏州亚培克生物科技有限公司 | 2016-10-26 | — | — | CN | claimed |
| CN-105384611-A | Electron donor of Ziegler-Natta catalyst and preparation method of electron donor | SUZHOU APAC BIOLOGICAL SCIENCE & TECH CO LTD | 2016-03-09 | — | — | CN | claimed |
| WO-2024071045-A1 | POLYCARBONATE RESIN AND MOLDED ARTICLE CONTAINING SAME | 富士フイルム株式会社 | 2024-04-04 | — | — | WO | disclosed |
| EP-3183250-B1 | PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL | CLAP CO LTD (KR) | 2023-10-04 | — | — | EP | disclosed |
| CN-111372557-B | 1, 3-propylene ether derived compounds for personal care | 禾大公司 | 2023-06-16 | — | — | CN | disclosed |
| US-11655264-B2 | Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil | APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) | 2023-05-23 | — | — | US | disclosed |
| WO-2023078950-A1 | LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY | ZIPHIUS VACCINES NV (BE) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023078946-A1 | LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY | ZIPHIUS VACCINES NV (BE) | 2023-05-11 | — | — | WO | disclosed |
| WO-2023078954-A1 | LIPID NANOPARTICLES FOR OLIGONUCLEOTIDE DELIVERY | ZIPHIUS VACCINES NV (BE) | 2023-05-11 | — | — | WO | disclosed |
| WO-1994029325-A1 | ANTIMICROBIAL SILOXANE QUATERNARY AMMONIUM SALTS | KIMBERLY-CLARK CORPORATION (US) | 1994-12-22 | — | — | WO | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0305114-A1 | Heat treating oil | NIPPON OIL CO. LTD. (JP) | 1989-03-01 | — | — | EP | disclosed |
| US-4396519-A | Alkyl-substituted bicycloalkyl ethers as useful lubricants and lubricating oils containing said ethers | TEXACO INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4365096-A | Alkyl-substituted bicycloalkyl ethers | TEXACO INC. (US) | 1982-12-21 | — | — | US | disclosed |
| US-4225449-A | HYDROCARBYLSULFONYL OR SULFINYL ALKANOL | EDWIN COOPER, INC. (US) | 1980-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655264-B2 | Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil | POLM, POLA1, POLD1 | TSHR 3352/4885THRB 1574/4885FAAH 1840/4885 |
| US-20180258112-A1 | Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil | POLM, POLA1, POLD1 | TSHR 3352/4885THRB 1574/4885FAAH 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.