Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10179591 | 1.00 | CA1 (0.43) | CA1CA2CA9PTPN1TYR | |
| SCHEMBL6282017 | 0.88 | TYR (0.51) | TYRSLC5A2ACHEGAA | |
| SCHEMBL6282046 | 0.83 | SLC5A2 (0.46) | TYRSLC5A2ACHE | |
| SCHEMBL10180096 | 0.82 | TYR (0.46) | TYRSLC5A2ACHEGAA | |
| SCHEMBL12500750 | 0.82 | TYR (0.46) | TYRSLC5A2ACHEGAA | |
| SCHEMBL10305226 | 0.82 | TYR (0.46) | TYRSLC5A2ACHEGAA | |
| SCHEMBL6282545 | 0.72 | EPHX2 (0.36) | CA9PTPN1SLC5A2GAA | |
| Sulfuric Acid SCHEMBL9220652 | 0.72 | GAA (0.51) | CA2GAA | |
| SCHEMBL14975518 | 0.70 | SLC5A2 (0.61) | TYRSLC5A2ACHEGAA | |
| SCHEMBL14975517 | 0.70 | SLC5A2 (0.61) | TYRSLC5A2ACHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012093091-A2 | NEW SACCHARIDE MIMICS AND THEIR USE AS INHIBITORS OF ANGIOGENESIS AND METASTASIS FORMATION | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2012-07-12 | — | — | WO | disclosed |
| EP-2474552-A1 | New saccharide mimics and their use as inhibitors of angiogenesis and metastasis formation | Deutsches Krebsforschungszentrum (DE) | 2012-07-11 | — | — | EP | disclosed |