Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CCR2 | P41597 | 16/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10223162 | 0.93 | CYP2C9 (0.63) | CYP2C9CCR2CYP3A4KCNH2 | |
| SCHEMBL306522 | 0.90 | CYP2C9 (0.67) | CYP2C9CCR2CYP3A4KCNH2 | |
| SCHEMBL13623777 | 0.90 | CYP2C9 (0.61) | CYP2C9CCR2CYP3A4KCNH2 | |
| SCHEMBL305754 | 0.89 | CYP2C9 (0.66) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL305568 | 0.89 | CYP2C9 (0.65) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL304326 | 0.87 | CYP2C9 (0.59) | CYP2C9CCR2CYP3A4KCNH2 | |
| SCHEMBL10223161 | 0.86 | CYP2C9 (0.61) | CYP2C9CCR2CYP3A4KCNH2 | |
| SCHEMBL10223262 | 0.86 | CYP2C9 (0.64) | CYP2C9CCR2CYP3A4 | |
| SCHEMBL305787 | 0.85 | CYP2C9 (0.63) | CYP2C9CCR2CYP3A4KCNH2 | |
| SCHEMBL10223306 | 0.84 | CYP2C9 (0.62) | CYP2C9CCR2CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474532-A1 | Heteroaryl sulfonamides and CCR2 | ChemoCentryx, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |