SCHEMBL10307995

SCHEMBL10307995

CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](C)NC1=O

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MC4R P32245 20/20 0.64
MC3R P41968 6/20 0.62
MC1R Q01726 5/20 0.62
MC5R P33032 5/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13063961 1.00 MC4R (0.64) MC4RMC3RMC1RMC5R
SCHEMBL10307976 0.97 MC4R (0.67) MC4RMC3RMC1RMC5R
SCHEMBL19473781 0.97 MC4R (0.67) MC4RMC3RMC1RMC5R
SCHEMBL13063967 0.97 MC4R (0.67) MC4RMC3RMC1RMC5R
SCHEMBL10308009 0.97 MC4R (0.66) MC4RMC3RMC1RMC5R
SCHEMBL10307900 0.97 MC4R (0.66) MC4RMC3RMC1RMC5R
SCHEMBL10307962 0.97 MC4R (0.66) MC4RMC3RMC1RMC5R
SCHEMBL10308020 0.97 MC4R (0.66) MC4RMC3RMC1RMC5R
SCHEMBL10308005 0.97 MC4R (0.66) MC4RMC3RMC1RMC5R
SCHEMBL19473838 0.97 MC4R (0.66) MC4RMC3RMC1RMC5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10632171-B2 Melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2020-04-28 US disclosed
US-20190216887-A1 Melanocortin Receptor-Specific Peptides PALATIN TECHNOLOGIES INC (US) 2019-07-18 US disclosed
US-10179804-B2 Melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2019-01-15 US disclosed
EP-2440227-B1 MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES PALATIN TECHNOLOGIES INC (US) 2017-10-18 EP disclosed
US-20160318977-A1 Melanocortin Receptor-Specific Peptides PALATIN TECHNOLOGIES INC (US) 2016-11-03 US disclosed
US-9458201-B2 Melanocortin receptor-specific heptapeptides PALATIN TECHNOLOGIES, INC. (US) 2016-10-04 US disclosed
US-20140357575-A1 Melanocortin Receptor-Specific Heptapeptides PALATIN TECHNOLOGIES INC (US) 2014-12-04 US disclosed
US-8846601-B2 Melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2014-09-30 US disclosed
US-20120178701-A1 Melanocortin Receptor-Specific Peptides PALATIN TECHNOLOGIES, INC. (US) 2012-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10179804-B2 Melanocortin receptor-specific peptides MC1R, MC3R, MC5R MC4R 4/4885MC3R 2/4885MC1R 1/4885
US-20140357575-A1 Melanocortin Receptor-Specific Heptapeptides MC5R, MC1R, MC3R MC4R 5/4885MC3R 3/4885MC1R 2/4885
US-20190216887-A1 Melanocortin Receptor-Specific Peptides MC1R, MC3R, MC4R MC4R 3/4885MC3R 2/4885MC1R 1/4885
US-20160318977-A1 Melanocortin Receptor-Specific Peptides MC1R, MC3R, MC5R MC4R 4/4885MC3R 2/4885MC1R 1/4885
US-10632171-B2 Melanocortin receptor-specific peptides MC1R, MC3R, MC4R MC4R 3/4885MC3R 2/4885MC1R 1/4885
US-20120178701-A1 Melanocortin Receptor-Specific Peptides MC1R, MC3R, MC5R MC4R 4/4885MC3R 2/4885MC1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.