⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1556234 | 0.83 | — | — | |
| SCHEMBL9451456 | 0.81 | — | — | |
| SCHEMBL31467887 | 0.79 | CYP1A2 (0.64) | — | |
| SCHEMBL8188242 | 0.79 | CYP1A2 (0.64) | — | |
| SCHEMBL1114673 | 0.79 | CYP1A2 (0.64) | — | |
| SCHEMBL2025525 | 0.73 | — | — | |
| SCHEMBL8803 | 0.73 | — | — | |
| SCHEMBL9719198 | 0.73 | — | — | |
| SCHEMBL8945449 | 0.73 | MAPT (0.39) | — | |
| SCHEMBL29123190 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250205232-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-26 | — | — | US | disclosed |
| US-20250052765-A1 | Nanobody Discovery Platform and Related Methods | CARNEGIE MELLON UNIVERSITY | 2025-02-13 | — | — | US | disclosed |
| US-12168009-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-12-17 | — | — | US | disclosed |
| US-11730726-B2 | Dimeric immuno-modulatory compounds against cereblon-based mechanisms | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-11730726-B2 | Dimeric immuno-modulatory compounds against cereblon-based mechanisms | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20230233560-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-07-27 | — | — | US | disclosed |
| WO-2023111983-A1 | NANOBODY DISCOVERY PLATFORM AND RELATED METHODS | CARNEGIE MELLON UNIVERSITY (US) | 2023-06-22 | — | — | WO | disclosed |
| US-11426407-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-08-30 | — | — | US | disclosed |
| US-11078214-B2 | Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of same | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2021-08-03 | — | — | US | disclosed |
| WO-2021126974-A1 | BIFUNCTIONAL AGENTS FOR PROTEIN RECRUITMENT AND/OR DEGRADATION | ORIONIS BIOSCIENCES, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| US-4847303-A | UNSATURATED KETONES | THE PROCTER & GAMBLE COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0322004-A1 | Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds | THE PROCTER & GAMBLE COMPANY (US) | 1989-06-28 | — | — | EP | disclosed |
| EP-0321432-A1 | Process for the preparation of certain substituted aromatic compounds | Norwich Eaton Pharmaceuticals, Inc. (US) | 1989-06-21 | — | — | EP | disclosed |
| EP-0318090-A2 | Tert-butyl phenyl compounds as anti-inflammatory agents | THE PROCTER & GAMBLE COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4734424-A | ANTICOAGULANTS | E. R. SQUIBB & SONS, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4724236-A | FOR TREATING THROMBOEBOLIC DISEASE, BRADYCARDIA OR BRADYARRYTHMIA | KARL THOMAE GMBH (DE) | 1988-02-09 | — | — | US | disclosed |
| US-4663336-A | ANTICOAGULANTS | E. R. SQUIBB & SONS, INC. (US) | 1987-05-05 | — | — | US | disclosed |
| US-4654355-A | 7-oxabicycloheptane substituted amide-thioamide prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1987-03-31 | — | — | US | disclosed |
| US-4638012-A | 7-oxabicycloheptane α-substituted ketone prostaglandin analogs useful in the treatment of thrombotic disease | E. R. SQUIBB & SONS, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0207684-A2 | 7-Oxabicycloheptane substituted diamide and its congener prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1987-01-07 | — | — | EP | disclosed |