⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959773 | 0.82 | TP53 (0.41) | — | |
| SCHEMBL3210792 | 0.78 | BACE1 (0.33) | — | |
| SCHEMBL9673372 | 0.77 | CA1 (0.37) | — | |
| SCHEMBL1301197 | 0.77 | CA12 (0.37) | — | |
| SCHEMBL275849 | 0.74 | — | — | |
| SCHEMBL123985 | 0.74 | CA1 (0.48) | — | |
| SCHEMBL164522 | 0.73 | — | — | |
| SCHEMBL160523 | 0.73 | — | — | |
| SCHEMBL1068357 | 0.73 | — | — | |
| SCHEMBL10530444 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074044-A2 | SYNAPTOJANIN-2 INHIBITORS AND USES THEREOF | Yeda Research and Development Co., Ltd. (IL) | 2016-10-05 | — | — | EP | claimed |
| WO-2015079413-A2 | SYNAPTOJANIN-2 INHIBITORS AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-06-04 | — | — | WO | claimed |
| EP-2487175-A1 | PHARMACEUTICAL PRODUCT CONTAINING AROMATIC HETEROCYCLIC COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2012-08-15 | — | — | EP | claimed |
| US-20120196854-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AROMATIC HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-08-02 | — | — | US | claimed |
| US-7811637-B2 | Silicon-containing polymer, process for producing the same, heat-resistant resin composition, and heat-resistant film | TOAGOSEI CO., LTD. (JP) | 2010-10-12 | — | — | US | claimed |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | claimed |
| EP-1453800-A2 | PROTEIN KINASE INHIBITORS | Abbott Laboratories (US) | 2004-09-08 | — | — | EP | claimed |
| WO-2003051838-A2 | PROTEIN KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2003-06-26 | — | — | WO | claimed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| EP-0778305-B1 | Hydroxyphenyl-containing polyorganosiloxanes | DOW CORNING TORAY SILICONE (JP) | 1999-04-07 | — | — | EP | claimed |
| US-5726271-A | Hydroxyphenyl-containing polyorganosiloxanes | DOW CORNING TORAY SILICONE, LTD. (JP) | 1998-03-10 | — | — | US | claimed |
| EP-0778305-A1 | Hydroxyphenyl-containing polyorganosiloxanes | Dow Corning Toray Silicone Company, Limited (JP) | 1997-06-11 | — | — | EP | claimed |
| EP-0413528-B1 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | YU RUEY J (US) | 1995-11-15 | — | — | EP | claimed |
| JP-3068517-A | — | — | None | — | — | JP | disclosed |
| CN-117825559-A | Radix tetrastigme decoction pieces produced by Min and detection method thereof, and production place identification method | 宁化县益珍农业科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-114540846-B | Synthesis method of 1,2, 4-triazolo six-membered nitrogen heterocycle-3-amine | 五邑大学 | 2023-09-19 | — | — | CN | disclosed |
| EP-0173126-A1 | Process for preparing novel dihydropyridine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |
| US-4460800-A | Process for preparation of hydroxyaryldialkylcarbinols | GENERAL ELECTRIC COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4460798-A | Process for preparation of asymmetrical bisphenols | GENERAL ELECTRIC COMPANY (US) | 1984-07-17 | — | — | US | disclosed |