SCHEMBL10312089

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10312101	0.93	HRH4 (0.48)	HRH4IDH2KDRKMT2APLK4
	SCHEMBL10312094	0.91	HRH4 (0.59)	HRH4KDRKMT2APLK4PAK4
	SCHEMBL10312099	0.90	HRH4 (0.46)	HRH4KMT2APOLBJAK2NTRK1
	SCHEMBL10312144	0.90	HRH4 (0.47)	HRH4IDH2KDRKMT2APOLB
	SCHEMBL16556869	0.90	AURKA (0.38)	HRH4IDH2KDRKMT2APOLB
	SCHEMBL10312086	0.89	HRH4 (0.48)	HRH4IDH2KDRKMT2APOLB
	SCHEMBL10312230	0.89	IDH2 (0.52)	HRH4IDH2KDRKMT2APOLB
	SCHEMBL10312213	0.88	HRH4 (0.41)	HRH4KDRKMT2APLK4PAK4
	SCHEMBL10312113	0.88	HRH4 (0.55)	HRH4KDRKMT2APLK4PAK4
	SCHEMBL10312103	0.88	HRH4 (0.47)	HRH4KDRKMT2APLK4PAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.