SCHEMBL10312124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10312234	0.91	HRH4 (0.61)	HRH4USP2SMN1; SMN2IDH2MAPT
	SCHEMBL10312183	0.91	HRH4 (0.51)	HRH4USP2SMN1; SMN2IDH2CHRNA7
	SCHEMBL10312215	0.90	HRH4 (0.48)	HRH4CHRNA7PLK4AURKAABL1
	SCHEMBL16556933	0.90	HRH4 (0.51)	HRH4USP2SMN1; SMN2IDH2MAPT
	SCHEMBL10312147	0.88	HRH4 (0.48)	HRH4USP2SMN1; SMN2MAPTPLK4
	SCHEMBL10312230	0.88	IDH2 (0.52)	HRH4USP2SMN1; SMN2IDH2MAPT
	SCHEMBL10312231	0.87	HRH4 (0.49)	HRH4USP2SMN1; SMN2IDH2MAPT
	SCHEMBL10312226	0.87	HRH4 (0.47)	HRH4USP2SMN1; SMN2IDH2MAPT
	SCHEMBL10312151	0.87	HRH4 (0.49)	HRH4USP2SMN1; SMN2IDH2MAPT
	SCHEMBL10312125	0.82	HRH4 (0.44)	HRH4USP2SMN1; SMN2IDH2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.