Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 5/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 4/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 4/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10312166 | 0.93 | HRH4 (0.44) | IGF1RHRH4PAK4PAK1 | |
| SCHEMBL10312209 | 0.93 | HRH4 (0.54) | IGF1RHRH4PAK4PAK1INSR | |
| SCHEMBL10312157 | 0.92 | IGF1R (0.47) | IGF1RHRH4PAK4PAK1 | |
| SCHEMBL10312164 | 0.92 | HRH4 (0.57) | IGF1RHRH4PAK4PAK1INSR | |
| SCHEMBL10312082 | 0.90 | HRH4 (0.44) | IGF1RHRH4PAK4PAK1 | |
| SCHEMBL10312128 | 0.89 | PAK4 (0.47) | IGF1RHRH4PAK4PAK1 | |
| SCHEMBL10312091 | 0.89 | HRH4 (0.45) | IGF1RHRH4PAK4PAK1 | |
| SCHEMBL10312180 | 0.89 | HRH4 (0.48) | IGF1RHRH4 | |
| SCHEMBL10312092 | 0.87 | HRH4 (0.39) | IGF1RHRH4PAK4PAK1 | |
| SCHEMBL10312222 | 0.86 | HRH4 (0.50) | IGF1RHRH4PAK4PAK1INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178758-A1 | STYRYL-TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CALIFORNIA CAPITAL EQUITY, LLC (US) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178758-A1 | STYRYL-TRIAZINE DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | STK25, STK35, SGK2 | IGF1R 1148/4885HRH4 2393/4885PAK4 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.