SCHEMBL10312170

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10312196	0.97	HRH4 (0.57)	HRH4IGF1RPAK4PAK1PLK4
	SCHEMBL10312128	0.93	PAK4 (0.47)	HRH4IGF1RPAK4PAK1
	SCHEMBL10312209	0.91	HRH4 (0.54)	HRH4IGF1RPAK4PAK1PLK4
	SCHEMBL10312108	0.89	HRH4 (0.57)	HRH4PAK4PAK1PLK4AURKA
	SCHEMBL10312233	0.88	HRH4 (0.56)	HRH4IGF1RPAK4PAK1PLK4
	SCHEMBL10312202	0.88	PAK4 (0.45)	HRH4IGF1RPAK4PAK1
	SCHEMBL10312139	0.87	AURKA (0.54)	HRH4IGF1RPAK4PAK1PLK4
	SCHEMBL10312117	0.87	HRH4 (0.45)	HRH4IGF1RPAK4PAK1
	SCHEMBL10312142	0.87	HRH4 (0.55)	HRH4PAK4PAK1PLK4AURKA
	SCHEMBL10312164	0.87	HRH4 (0.57)	HRH4IGF1RPAK4PAK1PLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.