Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 3/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34474814 | 1.00 | SYK (0.33) | SYKTSHRGAANOS1METAP1 | |
| SCHEMBL30929643 | 0.83 | FEN1 (0.32) | TSHRGAA | |
| SCHEMBL10700161 | 0.80 | GAA (0.38) | SYKTSHRGAAPDE4A | |
| SCHEMBL1115312 | 0.76 | — | — | |
| SCHEMBL18656078 | 0.76 | — | — | |
| SCHEMBL13415961 | 0.76 | — | — | |
| SCHEMBL19486191 | 0.72 | SYK (0.34) | SYKTSHRGAAPDE4APDE4B | |
| SCHEMBL1777044 | 0.72 | — | — | |
| SCHEMBL1202062 | 0.72 | — | — | |
| SCHEMBL1777117 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952010-B2 | Amino group-containing pyrrolidinone derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | disclosed |
| US-20140187542-A1 | AMINO GROUP-CONTAINING PYRROLIDINONE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-07-03 | — | — | US | disclosed |
| US-20130261194-A1 | Functionalized Water-Soluble Polyphosphazenes and Uses Thereof as Modifiers of Biological Agents | ANDRIANOV ALEXANDER K (US) | 2013-10-03 | — | — | US | disclosed |
| US-20120172455-A1 | Functionalized water-soluble polyphosphazenes and uses thereof as modifiers of biological agents | ANDRIANOV ALEXANDER K (US) | 2012-07-05 | — | — | US | disclosed |
| US-20100298525-A1 | Functionalized water-soluble polyphosphazenes and uses thereof as modifiers of biological agents | ANDRIANOV ALEXANDER K | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187542-A1 | AMINO GROUP-CONTAINING PYRROLIDINONE DERIVATIVE | AR, RCC2, NR3C2 | SYK 3882/4885TSHR 2590/4885GAA 4800/4885 |
| US-20120172455-A1 | Functionalized water-soluble polyphosphazenes and uses thereof as modifiers of biological agents | PHOSPHO1, CD47, ACP1 | SYK 202/4885TSHR 3285/4885GAA 1953/4885 |
| US-20100298525-A1 | Functionalized water-soluble polyphosphazenes and uses thereof as modifiers of biological agents | PHOSPHO1, CD47, ACP1 | SYK 202/4885TSHR 3285/4885GAA 1953/4885 |
| US-20130261194-A1 | Functionalized Water-Soluble Polyphosphazenes and Uses Thereof as Modifiers of Biological Agents | PHOSPHO1, CD47, ACP1 | SYK 202/4885TSHR 3285/4885GAA 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.