Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.54 |
| ▸ | CDC25B | P30305 | 14/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.54 |
| ▸ | CDC25A | P30304 | 4/20 | 0.54 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12869084 | 1.00 | PTPN1 (0.54) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314126 | 1.00 | PTPN1 (0.54) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314148 | 0.92 | PTPN1 (0.48) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314144 | 0.92 | PTPN1 (0.54) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314149 | 0.87 | PTPN1 (0.49) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314128 | 0.86 | PTPN1 (0.51) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314125 | 0.86 | PTPN1 (0.51) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314150 | 0.85 | PTPN1 (0.54) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL1171495 | 0.83 | PTPN1 (0.53) | PTPN1CDC25BPTPN2CDC25APTPN6 | |
| SCHEMBL10314138 | 0.82 | PTPN1 (0.48) | PTPN1CDC25BPTPN2CDC25APTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211859-B2 | α-galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-07-03 | — | — | US | disclosed |