Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 0.45 |
| ▸ | RAB9A | P51151 | 15/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10315335 | 1.00 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10315096 | 0.99 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10315332 | 0.99 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10315105 | 0.94 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10315341 | 0.94 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10315112 | 0.93 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10315353 | 0.93 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10315100 | 0.92 | ATR (0.43) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL10315346 | 0.92 | ATR (0.43) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12721937 | 0.90 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216696-B2 | Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-8216696-B2 | Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20090153041-A1 | Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device and Electronic Appliance Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-06-18 | — | — | US | disclosed |
| US-20090153041-A1 | Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device and Electronic Appliance Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090153041-A1 | Quinoxaline Derivative, and Light Emitting Element, Light Emitting Device and Electronic Appliance Using the Same | SLC1A2, SLC18A2, SLC18A3 | NPC1 3369/4885RAB9A 979/4885SMN1; SMN2 4124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.