SCHEMBL10315433

SCHEMBL10315433

Cc1cc(C)c(-c2ccc(-c3c(C)cc(C)cc3C)c3nc(-c4ccc(N(c5ccccc5)c5ccc(-c6nc7ccccc7o6)cc5)cc4)c(-c4ccc(N(c5ccccc5)c5ccc(-c6nc7ccccc7o6)cc5)cc4)nc23)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.42
SMN1; SMN2 Q16637 8/20 0.42
KDM4E B2RXH2 7/20 0.42
HPGD P15428 7/20 0.42
RAB9A P51151 7/20 0.42
CASP3 P42574 2/20 0.42
SENP8 Q96LD8 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
SENP6 Q9GZR1 2/20 0.42
POLB P06746 1/20 0.42
ALDH1A1 P00352 6/20 0.41
HSD17B10 Q99714 4/20 0.41
TP53 P04637 3/20 0.41
MAPT P10636 6/20 0.41
USP2 O75604 2/20 0.41
HCRTR1 O43613 2/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RXFP1 Q9HBX9 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10315199 0.99 NPC1 (0.44) NPC1SMN1; SMN2KDM4EHPGDRAB9A
SCHEMBL10315423 0.91 NPC1 (0.43) NPC1SMN1; SMN2KDM4EHPGDRAB9A
SCHEMBL10125940 0.91 NPC1 (0.49) NPC1SMN1; SMN2KDM4EHPGDRAB9A
SCHEMBL10126065 0.90 NPC1 (0.47) NPC1SMN1; SMN2KDM4EHPGDRAB9A
SCHEMBL10315200 0.90 NPC1 (0.44) NPC1SMN1; SMN2KDM4EHPGDRAB9A
SCHEMBL10315421 0.90 NPC1 (0.45) NPC1SMN1; SMN2KDM4EHPGDRAB9A
SCHEMBL10315198 0.89 NPC1 (0.45) NPC1SMN1; SMN2KDM4EHPGDRAB9A
SCHEMBL10315209 0.89 NPC1 (0.44) NPC1SMN1; SMN2KDM4EHPGDRAB9A
SCHEMBL10315725 0.88 NPC1 (0.43) NPC1SMN1; SMN2KDM4EHPGDRAB9A
SCHEMBL10315428 0.87 PTPN2 (0.46) NPC1SMN1; SMN2KDM4EHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2067778-B1 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LAB (JP) 2016-08-17 EP disclosed
US-8216696-B2 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-10 US disclosed
US-8216696-B2 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-10 US disclosed