SCHEMBL10315435

SCHEMBL10315435

c1ccc(-c2ccc(N(c3ccc(-c4nc5ccccc5o4)cc3)c3ccc(-c4nc5ccccc5nc4-c4ccc(N(c5ccc(-c6ccccc6)cc5)c5ccc(-c6nc7ccccc7o6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.54
RAB9A P51151 5/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
ATM Q13315 1/20 0.54
HSD17B10 Q99714 4/20 0.50
HPGD P15428 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 3/20 0.50
TP53 P04637 1/20 0.50
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MMP13 P45452 1/20 0.48
MAPT P10636 3/20 0.46
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN5 P54829 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10315217 1.00 NPC1 (0.54) NPC1RAB9AMEN1KMT2AATM
SCHEMBL10315245 0.99 NPC1 (0.52) NPC1RAB9AMEN1KMT2AATM
SCHEMBL10315210 0.99 NPC1 (0.52) NPC1RAB9AMEN1KMT2AATM
SCHEMBL10315242 0.99 NPC1 (0.52) NPC1RAB9AMEN1KMT2AATM
SCHEMBL10315455 0.97 NPC1 (0.54) NPC1RAB9AMEN1KMT2AATM
SCHEMBL10315466 0.97 NPC1 (0.54) NPC1RAB9AMEN1KMT2AATM
SCHEMBL4248096 0.97 NPC1 (0.54) NPC1RAB9AMEN1KMT2AATM
SCHEMBL10315399 0.96 NPC1 (0.55) NPC1RAB9AMEN1KMT2AATM
SCHEMBL22791803 0.93 NPC1 (0.61) NPC1RAB9AMEN1KMT2AATM
SCHEMBL22791796 0.93 NPC1 (0.61) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2067778-B1 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LAB (JP) 2016-08-17 EP disclosed
US-8216696-B2 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-10 US disclosed
US-8216696-B2 Quinoxaline derivative, and light emitting element, light emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-07-10 US disclosed
EP-2067778-A1 Quinoxaline derivative, and light emitting element, licht emitting device and electronic appliance using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-06-10 EP disclosed