Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 13/20 | 0.64 |
| ▸ | FLT3 | P36888 | 7/20 | 0.62 |
| ▸ | KIT | P10721 | 4/20 | 0.62 |
| ▸ | CSF1R | P07333 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031646 | 0.86 | PDGFRB (0.75) | PDGFRBFLT3KITCSF1R | |
| SCHEMBL1028739 | 0.85 | PDGFRB (0.75) | PDGFRBFLT3KIT | |
| SCHEMBL1030345 | 0.81 | PDGFRB (0.60) | PDGFRBFLT3KIT | |
| SCHEMBL13956853 | 0.80 | FLT3 (0.79) | PDGFRBFLT3KITCSF1R | |
| SCHEMBL1030943 | 0.80 | PDGFRB (0.60) | PDGFRBFLT3KIT | |
| SCHEMBL2923104 | 0.78 | PDGFRB (1.00) | PDGFRBFLT3KITCSF1R | |
| SCHEMBL13524740 | 0.78 | PDGFRB (0.88) | PDGFRBFLT3KITCSF1R | |
| SCHEMBL13524742 | 0.78 | PDGFRB (0.88) | PDGFRBFLT3KITCSF1R | |
| SCHEMBL13956852 | 0.77 | FLT3 (1.00) | PDGFRBFLT3KIT | |
| SCHEMBL27734244 | 0.77 | FLT3 (1.00) | PDGFRBFLT3KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067123-B1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |