⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL118500 | 0.83 | — | — | |
| Iodomethane SCHEMBL799995 | 0.83 | — | — | |
| Iodomethane SCHEMBL87147 | 0.83 | — | — | |
| Iodomethane SCHEMBL28473371 | 0.77 | — | — | |
| Iodomethane SCHEMBL3415879 | 0.72 | — | — | |
| Ethane SCHEMBL29691387 | 0.55 | — | — | |
| Ethane SCHEMBL1331172 | 0.55 | — | — | |
| Ethane SCHEMBL4877482 | 0.55 | — | — | |
| Ethane SCHEMBL18184927 | 0.55 | — | — | |
| Ethane SCHEMBL21175041 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059200-A1 | PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2025-02-20 | — | — | US | disclosed |
| EP-4413012-A1 | PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE | Studiengesellschaft Kohle gGmbH (DE) | 2024-08-14 | — | — | EP | disclosed |
| WO-2023110394-A1 | PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| EP-4198038-A1 | PROCESS FOR C-H INSERTION BY GEM-HYDROGENATION OF AN INTERNAL ALKYNE | Studiengesellschaft Kohle mbH (DE) | 2023-06-21 | — | — | EP | disclosed |
| CN-114276340-B | Chlorobenzoxazole derivative or pharmaceutically acceptable salt thereof and application thereof | 郑州大学 | 2022-10-04 | — | — | CN | disclosed |
| CN-114276340-A | Chlorobenzoxazole derivative or pharmaceutically acceptable salt thereof and application thereof | 郑州大学 | 2022-04-05 | — | — | CN | disclosed |
| EP-2620433-B1 | SUBSTITUTED AMIDE COMPOUND | ASTELLAS PHARMA INC (JP) | 2015-05-13 | — | — | EP | disclosed |
| EP-2481725-B1 | SUBSTITUTED AMIDE COMPOUND | ASTELLAS PHARMA INC (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-8815920-B2 | Substituted amide compound | ASTELLAS PHARMA INC. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-8669246-B2 | Substituted amide compound | ASTELLAS PHARMA INC. (JP) | 2014-03-11 | — | — | US | disclosed |
| US-20130231320-A1 | SUBSTITUTED AMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2013-09-05 | — | — | US | disclosed |
| EP-2620433-A1 | SUBSTITUTED AMIDE COMPOUND | Astellas Pharma Inc. (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-2481725-A1 | SUBSTITUTED AMIDE COMPOUND | Astellas Pharma Inc. (JP) | 2012-08-01 | — | — | EP | disclosed |
| US-20120184521-A1 | SUBSTITUTED AMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-07-19 | — | — | US | disclosed |