Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CALML3 | P27482 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541523 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL541780 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL541619 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL541524 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL541557 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL541556 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL541522 | 0.93 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Cadazolid SCHEMBL541681 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Cadazolid SCHEMBL541618 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| Cadazolid SCHEMBL29379581 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2296651-B1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES FOR TREATING BACTERIAL INTESTINAL DISEASES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-07-18 | — | — | EP | claimed |