Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654199 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL25177393 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL9661373 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL15201346 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL25170995 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL25178329 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL25182074 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL25177400 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL25181456 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 | |
| SCHEMBL7571670 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8287846-B2 | Cosmetic or dermatological preparations comprising N-acetylcysteine | ZAMBON S.P.A. (IT) | 2012-10-16 | — | — | US | disclosed |
| EP-2046277-B1 | COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE | ZAMBON SPA (IT) | 2011-01-19 | — | — | EP | disclosed |
| US-20100021399-A1 | COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE | ZAMBON S.P.A (IT) | 2010-01-28 | — | — | US | disclosed |
| EP-2046277-A1 | COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE | ZAMBON S.p.A. (IT) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012220-A1 | COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING N-ACETYLCYSTEINE | ZAMBON S.P.A. (IT) | 2008-01-31 | — | — | WO | disclosed |
| EP-0497926-A1 | MULTI-SITE METAL CHELATING AGENTS | NYCOMED SALUTAR, INC. (US) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991005762-A1 | MULTI-SITE METAL CHELATING AGENTS | COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) | 1991-05-02 | — | — | WO | disclosed |