Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.54 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456433 | 0.90 | AKR1B1 (0.57) | AKR1B1PARK7KDM4EALOX15TSHR | |
| SCHEMBL11455808 | 0.89 | AKR1B1 (0.42) | AKR1B1PARK7KDM4EALOX15TSHR | |
| SCHEMBL11467885 | 0.87 | AKR1B1 (0.40) | AKR1B1ACHE | |
| SCHEMBL11467897 | 0.87 | AKR1B1 (0.40) | AKR1B1ACHEALDH1A1 | |
| SCHEMBL11457263 | 0.87 | TSHR (0.44) | AKR1B1TSHRACHEALDH1A1HPGD | |
| SCHEMBL11463851 | 0.86 | AKR1B1 (0.50) | AKR1B1PARK7KDM4EALOX15TSHR | |
| SCHEMBL11457865 | 0.85 | AKR1B1 (0.52) | AKR1B1PARK7KDM4EALOX15TSHR | |
| SCHEMBL11455791 | 0.85 | MEN1 (0.43) | AKR1B1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11464142 | 0.84 | AKR1B1 (0.44) | AKR1B1PARK7ALDH1A1PTGDR2 | |
| SCHEMBL11474317 | 0.84 | AKR1B1 (0.49) | AKR1B1PARK7KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230703-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-10-28 | — | — | US | claimed |
| WO-2014176460-A1 | METHODS OF TREATING BEHAVIORIAL AND/OR MENTAL DISORDERS | CHAU DAVID T (US) | 2014-10-30 | — | — | WO | disclosed |
| US-8486922-B2 | Composition | CHEN CHIEN-HUNG (TW) | 2013-07-16 | — | — | US | disclosed |
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | disclosed |
| US-4230703-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-10-28 | — | — | US | disclosed |