Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 13/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10322386 | 1.00 | HTR2A (0.49) | HTR2AOPRM1TMEM97CCR5 | |
| SCHEMBL341781 | 0.98 | HTR2A (0.51) | HTR2AOPRM1TMEM97CCR5 | |
| SCHEMBL341780 | 0.98 | HTR2A (0.51) | HTR2AOPRM1TMEM97CCR5 | |
| Oxalic Acid SCHEMBL5440095 | 0.93 | HTR2A (0.45) | HTR2AOPRM1TMEM97CCR5 | |
| Oxalic Acid SCHEMBL5440089 | 0.93 | HTR2A (0.45) | HTR2AOPRM1TMEM97CCR5 | |
| Oxalic Acid SCHEMBL10321673 | 0.92 | HTR2A (0.54) | HTR2AOPRM1 | |
| Oxalic Acid SCHEMBL10322999 | 0.92 | HTR2A (0.54) | HTR2AOPRM1 | |
| Oxalic Acid SCHEMBL10321675 | 0.92 | HTR2A (0.54) | HTR2AOPRM1 | |
| SCHEMBL340767 | 0.91 | HTR2A (0.47) | HTR2AOPRM1TMEM97CCR5 | |
| SCHEMBL340766 | 0.91 | HTR2A (0.47) | HTR2AOPRM1TMEM97CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140350064-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS MOUNTAIN LLC | 2014-11-27 | — | — | US | claimed |
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | claimed |
| EP-2983473-A2 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS Mountain Llc (US) | 2016-02-17 | — | — | EP | disclosed |
| US-20140350064-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS MOUNTAIN LLC | 2014-11-27 | — | — | US | disclosed |
| WO-2014144130-A2 | PHARMACEUTICAL COMPOSITION COMPRISING AN AMPK ACTIVATOR AND A SEROTONERGIC AGENT AND METHODS OF USE THEREOF | ALS MOUNTAIN LLC (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | disclosed |