Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 6/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10323718 | 0.86 | DYRK1A (0.68) | DYRK1ADYRK1B | |
| SCHEMBL10323717 | 0.86 | DYRK1A (0.68) | DYRK1ADYRK1B | |
| SCHEMBL10324084 | 0.85 | DYRK1A (0.48) | DYRK1ADYRK1BMAPK1LMNASMN1; SMN2 | |
| SCHEMBL10324514 | 0.81 | DYRK1A (0.49) | DYRK1ADYRK1BNPC1LMNAROCK2 | |
| SCHEMBL10446550 | 0.79 | DYRK1A (0.69) | DYRK1ADYRK1B | |
| SCHEMBL10446551 | 0.79 | DYRK1A (0.69) | DYRK1ADYRK1B | |
| SCHEMBL10323240 | 0.79 | DYRK1A (0.47) | DYRK1ADYRK1BLMNASMN1; SMN2 | |
| SCHEMBL10446987 | 0.78 | DYRK1A (0.68) | DYRK1ADYRK1B | |
| Hydrochloric Acid SCHEMBL10322306 | 0.78 | DYRK1A (0.68) | DYRK1ADYRK1B | |
| Hydrochloric Acid SCHEMBL10322304 | 0.78 | DYRK1A (0.68) | DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184542-A1 | PYRIDO PYRIMIDINES | ANDERSON KEVIN (US) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184542-A1 | PYRIDO PYRIMIDINES | TYMS, TYMP, DPYD | DYRK1A 654/4885DYRK1B 570/4885MCHR1 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.