SCHEMBL1032471

SCHEMBL1032471

O=C(O)c1ccccc1Oc1ccc2ccccc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
PARP1 P09874 1/20 0.56
PARG Q86W56 1/20 0.56
GAA P10253 1/20 0.54
RCE1 Q9Y256 1/20 0.54
MIF P14174 1/20 0.53
HTT P42858 1/20 0.53
KDM4E B2RXH2 5/20 0.50
POLB P06746 2/20 0.50
CTNNB1 P35222 1/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
ALDH1A1 P00352 4/20 0.49
HPGD P15428 4/20 0.49
TDP1 Q9NUW8 2/20 0.49
MAPT P10636 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5660471 0.89 KDM4E (0.62) MEN1KMT2AL3MBTL1PARP1PARG
SCHEMBL7010102 0.87 MEN1 (0.53) MEN1KMT2AL3MBTL1PARP1PARG
SCHEMBL22741861 0.87 PTPN1 (0.55) MEN1KMT2AL3MBTL1PARP1PARG
SCHEMBL28411450 0.85 CTNNB1 (0.66) MEN1KMT2AL3MBTL1GAAHTT
SCHEMBL28949650 0.85 GAA (0.53) MEN1KMT2AL3MBTL1PARP1PARG
SCHEMBL5657927 0.85 GAA (0.53) MEN1KMT2AL3MBTL1PARP1PARG
SCHEMBL28634306 0.84 POLB (0.61) HTTKDM4EPOLBCTNNB1ALDH1A1
SCHEMBL6130408 0.84 MEN1 (0.51) MEN1KMT2AL3MBTL1PARP1PARG
SCHEMBL28560551 0.84 KDM4E (0.63) KMT2AHTTKDM4EPOLBCTNNB1
SCHEMBL20346748 0.83 KDM4E (0.58) MEN1KMT2AL3MBTL1PARP1PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3263145-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2021-01-20 EP claimed
EP-1998825-B1 ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS BECTON DICKINSON CO (US) 2017-10-18 EP claimed
EP-1610767-B1 MORPHINE CONTROLLED RELEASE SYSTEM EGALET AS (DK) 2011-01-19 EP claimed
EP-1610768-B1 MATRIX COMPOSITIONS FOR CONTROLLED DELIVERY OF DRUG SUBSTANCES EGALET AS (DK) 2008-07-02 EP claimed
EP-1429734-B1 CONTROLLED RELEASE SOLID DISPERSIONS OF CARVEDILOL EGALET AS (DK) 2007-12-26 EP claimed
CN-104758253-A Technology for preparation of macromolecular microspheres NEXBIO INC 2015-07-08 CN disclosed
CN-103784408-A Technology for the preparation of microparticles ANSUN BIOPHARMA INC 2014-05-14 CN disclosed
CN-101848704-A Techniques for preparing microparticles NEXBIO INC 2010-09-29 CN disclosed
CN-101404980-A Preparation Technology of Macromolecular Microspheres NEXBIO INC (US) 2009-04-08 CN disclosed
US-4073912-A Piperidylidene derivatives of benzo-fused xanthenes, thioxanthenes and dibenzoxepins and antipsychotic use thereof SMITHKLINE CORPORATION (US) 1978-02-14 US disclosed