SCHEMBL1032818

SCHEMBL1032818

O=S(=O)(O)c1ccc2ccccc2c1.[NaH]

nearest known ligand 0.62

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.62
LMNA P02545 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.55
F2 P00734 2/20 0.55
PRSS1 P07477 2/20 0.55
PRSS2 P07478 2/20 0.55
PRSS3 P35030 2/20 0.55
MCOLN3 Q8TDD5 2/20 0.53
TSHR P16473 2/20 0.53
ALDH1A1 P00352 2/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
CASP6 P55212 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PKM P14618 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27440284 1.00 SNCA (0.62) SNCALMNAL3MBTL1F2PRSS1
SCHEMBL28057270 1.00 SNCA (0.62) SNCALMNAL3MBTL1F2PRSS1
SCHEMBL27732648 1.00 SNCA (0.62) SNCALMNAL3MBTL1F2PRSS1
SCHEMBL28275730 0.98 SNCA (0.65) SNCALMNAL3MBTL1F2PRSS1
SCHEMBL29857297 0.98 SNCA (0.65) SNCALMNAL3MBTL1F2PRSS1
Naphthalene SCHEMBL28216326 0.98 SNCA (0.65) SNCALMNAL3MBTL1F2PRSS1
SCHEMBL1556 0.98 SNCA (0.65) SNCALMNAL3MBTL1F2PRSS1
SCHEMBL304050 0.98 SNCA (0.65) SNCALMNAL3MBTL1F2PRSS1
SCHEMBL29357423 0.98 SNCA (0.65) SNCALMNAL3MBTL1F2PRSS1
Water SCHEMBL756081 0.96 SNCA (0.62) SNCALMNAL3MBTL1F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108998815-B Modified additive is used in a kind of preparation method of copper foil and copper foil production 广东嘉元科技股份有限公司 2019-09-17 CN claimed
CN-109371659-A A kind of preparation method of the thick and heavy type silk fabric based on digit printing 苏州印丝特纺织数码科技有限公司 2019-02-22 CN claimed
CN-108998815-A Modified additive is used in a kind of preparation method of copper foil and copper foil production 广东嘉元科技股份有限公司 2018-12-14 CN claimed
CN-107163615-A A kind of environment-friendly type Weak acid red dyestuff and preparation method thereof 金华恒利康化工有限公司 2017-09-15 CN claimed
US-7794587-B2 Method to alter coke morphology using metal salts of aromatic sulfonic acids and/or polysulfonic acids EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-09-14 US claimed
CN-1954053-B Fouling inhibition of thermal treatment of heavy oils EXXONMOBIL RES & ENG CO 2010-06-16 CN claimed
US-7704376-B2 Fouling inhibition of thermal treatment of heavy oils EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-04-27 US claimed
US-7594989-B2 Enhanced thermal upgrading of heavy oil using aromatic polysulfonic acid salts EXXONMOBILE RESEARCH AND ENGINEERING COMPANY (US) 2009-09-29 US claimed
US-20090184029-A1 in a delayed coking process of heavy oil; additives facilitate the formation of shot coke and inhibit the formation of sponge coke; predominantly free-flowing coke to avoid or minimize hot drums EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-07-23 US claimed
CN-1954052-A Inhibitor enhanced thermal upgrading of heavy oils EXXONMOBIL RES & ENG CO (US) 2007-04-25 CN claimed
CN-1954053-A Fouling inhibition of thermal treatment of heavy oils EXXONMOBIL RES & ENG CO (US) 2007-04-25 CN claimed
EP-1751256-A1 FOULING INHIBITION OF THERMAL TREATMENT OF HEAVY OILS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-02-14 EP claimed
EP-1751257-A2 INHIBITOR ENHANCED THERMAL UPGRADING OF HEAVY OILS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-02-14 EP claimed
WO-2005113726-A1 FOULING INHIBITION OF THERMAL TREATMENT OF HEAVY OILS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-12-01 WO claimed
WO-2005113727-A2 INHIBITOR ENHANCED THERMAL UPGRADING OF HEAVY OILS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-12-01 WO claimed
US-20050258070-A1 Fouling inhibition of thermal treatment of heavy oils EXXONMOBIL RESEARCH & ENGINEERING CO. 2005-11-24 US claimed
US-20050258071-A1 Enhanced thermal upgrading of heavy oil using aromatic polysulfonic acid salts EXXONMOBIL RESEARCH & ENGINEERING CO. 2005-11-24 US claimed
US-20240083817-A1 GEOPOLYMER COMPOSITE AND EXPANDABLE VINYL AROMATIC POLYMER GRANULATE AND EXPANDED VINYL AROMATIC POLYMER FOAM COMPRISING THE SAME SYNTHOS S.A. (PL) 2024-03-14 US disclosed
EP-0108654-A1 Sulfonic acid compound having cyclopentadiene skeleton and composition comprising same and cement JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1984-05-16 EP disclosed
EP-0087639-A2 Water soluble fluors E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-09-07 EP disclosed