SCHEMBL10328385

SCHEMBL10328385

C=C(C)c1nnco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14446927 0.76
SCHEMBL390835 0.67 TSHR (0.41)
SCHEMBL30674447 0.63 POLB (0.35)
SCHEMBL30586797 0.63 CES1 (0.38)
SCHEMBL9112425 0.62
SCHEMBL26938394 0.60 DAGLA (0.33)
SCHEMBL30449 0.60
SCHEMBL12906161 0.58 NOTUM (0.59)
SCHEMBL2096146 0.57
SCHEMBL9332908 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186896-A1 SHP2 INHIBITOR AND COMPOSITION AND APPLICATION THEREOF Betta Pharmaceuticals Co., Ltd (CN) 2023-05-31 EP disclosed
WO-2023023532-A2 ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS CHEMOCENTRYX, INC. (US) 2023-02-23 WO disclosed
US-10875996-B2 Methacrylic copolymer and molded article KURARAY CO., LTD. (JP) 2020-12-29 US disclosed
US-20200317902-A1 METHACRYLIC COPOLYMER AND MOLDED ARTICLE KURARAY CO., LTD. (JP) 2020-10-08 US disclosed
EP-3564275-A1 METHACRYLIC COPOLYMER AND MOLDED ARTICLE Kuraray Co., Ltd. (JP) 2019-11-06 EP disclosed
EP-2957579-B1 COPOLYMER AND MOLDED BODY KURARAY CO (JP) 2019-10-02 EP disclosed
US-10407524-B2 Copolymer and molded article KURARAY CO., LTD. (JP) 2019-09-10 US disclosed
US-10287380-B2 Copolymer, and molded article KURARAY CO., LTD. (JP) 2019-05-14 US disclosed
EP-3095800-B1 COPOLYMER, AND MOLDED ARTICLE KURARAY CO (JP) 2018-05-02 EP disclosed
US-9856342-B2 Copolymer and molded body KURARAY CO., LTD. (JP) 2018-01-02 US disclosed
US-20090326154-A1 Additives for Halopolymers SOLVAY SOLEXIS S.P.A. (IT) 2009-12-31 US disclosed
US-20090326154-A1 Additives for Halopolymers SOLVAY SOLEXIS S.P.A. (IT) 2009-12-31 US disclosed
US-7629483-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2009-12-08 US disclosed
US-7629483-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2009-12-08 US disclosed
US-20080194881-A1 Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives SOLVAY SOLEXIS S.P.A. (IT) 2008-08-14 US disclosed
US-20080194881-A1 Copolymers having functional end groups of sulfonyl fluorides and acyl fluorides; macromer promoters useful for both condensation and addition polymerizations for elastomers and polymershaving a crystal structure; mechanical properties; lubricants for magnetic disks; adhesives SOLVAY SOLEXIS S.P.A. (IT) 2008-08-14 US disclosed
US-7371900-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2008-05-13 US disclosed
US-7371900-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2008-05-13 US disclosed
US-7365229-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2008-04-29 US disclosed
US-7365229-B2 Peroxidic perfluoropolyethers SOLVAY SOLEXIS S.P.A. (IT) 2008-04-29 US disclosed