Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.50 |
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.39 |
| ▸ | MC4R known ✓ | P32245 | 1/20 | 0.34 |
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 0.34 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | EYA2 | O00167 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28354875 | 0.97 | TDP1 (0.50) | TDP1EYA2APPACELMNA | |
| SCHEMBL120640 | 0.94 | — | — | |
| SCHEMBL14890359 | 0.94 | TDP1 (0.58) | TDP1EYA2APPACELMNA | |
| SCHEMBL9306714 | 0.92 | TDP1 (0.55) | TDP1EYA2APPACELMNA | |
| Potassium SCHEMBL3894343 | 0.92 | TDP1 (0.55) | TDP1EYA2APPACELMNA | |
| SCHEMBL9304702 | 0.92 | TDP1 (0.55) | TDP1EYA2APPACELMNA | |
| SCHEMBL9306621 | 0.92 | TDP1 (0.55) | TDP1EYA2APPACELMNA | |
| SCHEMBL77671 | 0.92 | TDP1 (0.55) | TDP1EYA2APPACELMNA | |
| SCHEMBL9305268 | 0.92 | TDP1 (0.55) | TDP1EYA2APPACELMNA | |
| SCHEMBL9304543 | 0.92 | TDP1 (0.55) | TDP1EYA2APPACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 800 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3566693-B1 | EYE DEVICE | EYED PHARMA (BE) | 2021-02-17 | — | — | EP | claimed |
| EP-3566693-A1 | EYE DEVICE | EyeD Pharma (BE) | 2019-11-13 | — | — | EP | claimed |
| EP-3068372-B1 | EYE DEVICE | EYED PHARMA (BE) | 2019-05-08 | — | — | EP | claimed |
| US-9999595-B2 | Eye device | EYED PHARMA (BE) | 2018-06-19 | — | — | US | claimed |
| US-20160287513-A1 | EYE DEVICE | EYED PHARMA (BE) | 2016-10-06 | — | — | US | claimed |
| EP-3068372-A1 | EYE DEVICE | EyeD Pharma (BE) | 2016-09-21 | — | — | EP | claimed |
| EP-1737899-B1 | DENDRITIC POLYMERS WITH ENHANCED AMPLIFICATION AND INTERIOR FUNCTIONALITY | DENDRITIC NANOTECHNOLOGIES INC (US) | 2015-07-08 | — | — | EP | claimed |
| WO-2015071427-A1 | EYE DEVICE | EYED PHARMA (BE) | 2015-05-21 | — | — | WO | claimed |
| CN-101927002-B | Medicament and coating composition | ZHONG SHUGUANG | 2014-03-12 | — | — | CN | claimed |
| US-8609198-B2 | Pharmaceutical dose form with a patterned coating and method of making the same | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2013-12-17 | — | — | US | claimed |
| US-20040115268-A1 | Systemic delivery of antiviral agents | CONTROL DELIVERY SYSTEMS, INC. | 2004-06-17 | — | — | US | claimed |
| WO-2004050066-A1 | MICROSPHERES AND RELATED PROCESSES AND PHARMACEUTICAL COMPOSITIONS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2004-06-17 | — | — | WO | claimed |
| WO-2004043435-A2 | SYSTEMIC DELIVERY OF ANTIVIRAL AGENTS | CONTROL DELIVERY SYSTEMS, INC. (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2003092660-A1 | MONOCOMPARTMENT OSMOTIC CONTROLLED DRUG DELIVERY SYSTEM | RANBAXY LABORATORIES LIMITED (US) | 2003-11-13 | — | — | WO | claimed |
| WO-1996000074-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING VITAMIN-D ANALOGS | BEN-GURION UNIVERSITY OF THE NEGEV (IL) | 1996-01-04 | — | — | WO | claimed |
| US-5025004-A | Water-dispersible polymeric compositions | EASTMAN KODAK COMPANY (US) | 1991-06-18 | — | — | US | claimed |
| US-5008118-A | Contacting coating agent with core powder of organic material with sufficient frictional heating to cause adhesion | NIPPON OIL AND FATS (JP) | 1991-04-16 | — | — | US | claimed |
| EP-0063014-B1 | A METHOD OF PREPARING COATED SOLID PREPARATIONS | SANKYO COMPANY LIMITED (JP) | 1985-08-14 | — | — | EP | claimed |
| US-4533562-A | Method of preparing coated solid preparations | SANKYO COMPANY, LIMITED (JP) | 1985-08-06 | — | — | US | claimed |
| EP-0063014-A2 | A method of preparing coated solid preparations | SANKYO COMPANY LIMITED (JP) | 1982-10-20 | — | — | EP | claimed |