Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379586 | 0.75 | ADORA1 (0.56) | FLT4KDRHPGDTAAR1ALDH1A1 | |
| SCHEMBL5699095 | 0.74 | FLT4 (0.46) | FLT4KDRHPGDTAAR1ALDH1A1 | |
| SCHEMBL19987154 | 0.74 | FLT4 (0.46) | FLT4KDRHPGDTAAR1ALDH1A1 | |
| SCHEMBL9503851 | 0.74 | FLT4 (0.49) | FLT4KDRHPGDTAAR1ALDH1A1 | |
| SCHEMBL731404 | 0.72 | CYP2C9 (0.36) | ALDH1A1ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL12194499 | 0.71 | PI4KA (0.60) | FLT4KDRHPGDTAAR1ALDH1A1 | |
| SCHEMBL6364118 | 0.71 | ADORA2A (0.60) | FLT4KDRTAAR1PI4KAPI4K2B | |
| SCHEMBL17364335 | 0.71 | ADORA2A (0.60) | FLT4KDRHPGDTAAR1PI4KA | |
| SCHEMBL24205301 | 0.70 | FLT4 (0.43) | FLT4KDRHPGDTAAR1ALDH1A1 | |
| SCHEMBL22326753 | 0.70 | ADORA2A (0.46) | FLT4KDRHPGDTAAR1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365556-A1 | NUCLEOSIDE ANALOGUES. | GENENTECH INC (US) | 1990-05-02 | — | — | EP | claimed |
| WO-1988009796-A1 | NUCLEOSIDE ANALOGUES | GENENTECH, INC. (US) | 1988-12-15 | — | — | WO | claimed |