Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257586 | 1.00 | HSD17B10 (0.43) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 | |
| SCHEMBL4366731 | 1.00 | HSD17B10 (0.43) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 | |
| SCHEMBL4701343 | 0.98 | HSD17B10 (0.44) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 | |
| SCHEMBL9795829 | 0.92 | HSD17B10 (0.42) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 | |
| SCHEMBL26728273 | 0.88 | HSD17B10 (0.55) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 | |
| SCHEMBL14071038 | 0.88 | HSD17B10 (0.55) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 | |
| SCHEMBL26728265 | 0.88 | HSD17B10 (0.55) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 | |
| SCHEMBL13257581 | 0.88 | HSD17B10 (0.55) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 | |
| SCHEMBL26728250 | 0.88 | HSD17B10 (0.55) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 | |
| SCHEMBL26803177 | 0.88 | HSD17B10 (0.55) | HSD17B10KMT2ATARDBPALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387315-A1 | FLUORINATED ALKOXYL COMPOUNDS. | MERCK PATENT GMBH (DE) | 1990-09-19 | — | — | EP | disclosed |
| WO-1990001021-A1 | FLUORINATED ALKOXYL COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-02-08 | — | — | WO | disclosed |
| EP-0220254-A1 | BENZONITRILES. | MERCK PATENT GMBH (DE) | 1987-05-06 | — | — | EP | disclosed |
| WO-1986006372-A1 | BENZONITRILE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-11-06 | — | — | WO | disclosed |