Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683918 | 0.84 | MAPT (0.46) | MAPTCYP3A4KDM4EALDH1A1CA1 | |
| SCHEMBL10428228 | 0.82 | CA1 (0.62) | CYP3A4CA1CA2CA12CA7 | |
| SCHEMBL10681473 | 0.80 | CA1 (0.52) | MAPTCYP3A4KDM4EALDH1A1CA1 | |
| SCHEMBL31238916 | 0.79 | CNR2 (0.62) | MAPTCYP3A4KDM4EALDH1A1CA1 | |
| SCHEMBL11358739 | 0.78 | CA1 (0.50) | KDM4EALDH1A1CA1CA2CA12 | |
| Methyl Syringate SCHEMBL211747 | 0.78 | MEN1 (0.61) | MAPTCYP3A4KDM4EALDH1A1CA1 | |
| Syringate SCHEMBL159392 | 0.78 | CA12 (0.67) | MAPTCYP3A4KDM4EALDH1A1CA1 | |
| SCHEMBL2114318 | 0.78 | KMT2A (0.61) | MAPTCYP3A4KDM4EALDH1A1CA1 | |
| SCHEMBL11352076 | 0.77 | KDM4E (0.53) | MAPTKDM4EALDH1A1CA1CA2 | |
| SCHEMBL10683847 | 0.76 | KDM4E (0.53) | MAPTCYP3A4KDM4EALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908470-A | Process for the methyl-4-(dimethylamino)-3,5-dimethoxybenzoate | HOFFMAN-LA ROCHE INC. (US) | 1990-03-13 | — | — | US | claimed |
| JP-2000248-A | — | — | None | — | — | JP | disclosed |
| EP-0318825-A3 | Process for the preparation of 4-dimethylamino-3,5-dimethoxy-benzoic acid methyl ester | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-16 | — | — | EP | disclosed |
| US-4908470-A | Process for the methyl-4-(dimethylamino)-3,5-dimethoxybenzoate | HOFFMAN-LA ROCHE INC. (US) | 1990-03-13 | — | — | US | disclosed |
| US-4908470-A | Process for the methyl-4-(dimethylamino)-3,5-dimethoxybenzoate | HOFFMAN-LA ROCHE INC. (US) | 1990-03-13 | — | — | US | disclosed |
| US-4908470-A | Process for the methyl-4-(dimethylamino)-3,5-dimethoxybenzoate | HOFFMAN-LA ROCHE INC. (US) | 1990-03-13 | — | — | US | disclosed |
| JP-H02248-A | PREPARATION OF METHYL-4-(DIMETHYLAMINO)-3,5-DEMETHOXY BENZOATE | F HOFFMANN LA ROCHE AG | 1990-01-05 | — | — | JP | disclosed |
| EP-0318825-A2 | Process for the preparation of 4-dimethylamino-3,5-dimethoxy-benzoic acid methyl ester | F. HOFFMANN-LA ROCHE AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| US-4792557-A | 2,4-diamino-5[4-amino (or dimethylamino)-3,5-dimethoxybenzyl]pyrimidine and antibacterial composition thereof | HOFFMAN-LA ROCHE INC. (US) | 1988-12-20 | — | — | US | disclosed |
| US-4659818-A | Intermediates for benzylpyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1987-04-21 | — | — | US | disclosed |
| US-4515948-A | BACTERICIDES, SULFA DRUG POTENTIATORS | HOFFMANN-LA ROCHE INC. (US) | 1985-05-07 | — | — | US | disclosed |