Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 1.00 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.57 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10337787 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A | |
| SCHEMBL10337893 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A | |
| SCHEMBL10337783 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A | |
| SCHEMBL10337784 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A | |
| SCHEMBL10337594 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A | |
| SCHEMBL10337865 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A | |
| SCHEMBL10338012 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A | |
| SCHEMBL10338015 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A | |
| SCHEMBL10337989 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A | |
| SCHEMBL10337595 | 1.00 | ELANE (1.00) | ELANEPLA2G2APLA2G5FFAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365539-A4 | HUMAN LEUCOCYTE ELASTASE INHIBITOR COMPOUNDS | — | 1990-12-05 | — | — | EP | claimed |
| EP-0365539-A1 | HUMAN LEUCOCYTE ELASTASE INHIBITOR COMPOUNDS | AUSTRALIAN COMMERCIAL RESEARCH & DEVELOPMENT LIMITED (AU) | 1990-05-02 | — | — | EP | claimed |
| WO-1988010258-A1 | HUMAN LEUCOCYTE ELASTASE INHIBITOR COMPOUNDS | LA TROBE UNIVERSITY (AU) | 1988-12-29 | — | — | WO | claimed |