Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RARA | P10276 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062343 | 1.00 | HSD17B10 (0.51) | HSD17B10TSHRPPARARARBALDH1A1 | |
| SCHEMBL9061760 | 1.00 | HSD17B10 (0.51) | HSD17B10TSHRPPARARARBALDH1A1 | |
| SCHEMBL9061964 | 1.00 | HSD17B10 (0.51) | HSD17B10TSHRPPARARARBALDH1A1 | |
| SCHEMBL9061641 | 1.00 | HSD17B10 (0.51) | HSD17B10TSHRPPARARARBALDH1A1 | |
| SCHEMBL9061594 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRPPARARARBALDH1A1 | |
| SCHEMBL9060272 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRPPARARARBALDH1A1 | |
| SCHEMBL9061890 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRPPARARARBALDH1A1 | |
| SCHEMBL9060759 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRPPARARARBALDH1A1 | |
| SCHEMBL9060268 | 0.98 | HSD17B10 (0.50) | HSD17B10TSHRPPARARARBALDH1A1 | |
| SCHEMBL9060970 | 0.98 | PPARA (0.49) | HSD17B10TSHRPPARARARBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381728-A1 | DIFLUOROMETHYL COMPOUNDS. | MERCK PATENT GMBH (DE) | 1990-08-16 | — | — | EP | disclosed |
| WO-1990001056-A1 | DIFLUOROMETHYL COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-02-08 | — | — | WO | disclosed |