⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115759 | 1.00 | — | — | |
| SCHEMBL37136 | 0.95 | — | — | |
| Water SCHEMBL8848944 | 0.95 | — | — | |
| Water SCHEMBL8502324 | 0.91 | — | — | |
| SCHEMBL8895617 | 0.91 | — | — | |
| SCHEMBL23218025 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL6643669 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL21838765 | 0.91 | — | — | |
| SCHEMBL3269957 | 0.91 | — | — | |
| SCHEMBL4542253 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3981899-A | FROM TRIAMINOGUANIDINE AND POTASSIUM CYANOFORMATE, HIGH ENERGY FUELS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-09-21 | — | — | US | claimed |
| JP-2225452-A | — | — | None | — | — | JP | disclosed |
| CN-108295073-B | Polyfluoro compounds as bruton's tyrosine kinase inhibitors | 浙江导明医药科技有限公司 | 2020-06-16 | — | — | CN | disclosed |
| US-10300066-B2 | Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2019-05-28 | — | — | US | disclosed |
| US-20180207161-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2018-07-26 | — | — | US | disclosed |
| US-9861636-B2 | Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2018-01-09 | — | — | US | disclosed |
| US-20170065594-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2017-03-09 | — | — | US | disclosed |
| EP-3138842-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON'S TYROSINE KINASE INHIBITORS | Zhejiang DTRM Biopharma Co., Ltd. (CN) | 2017-03-08 | — | — | EP | disclosed |
| US-9532990-B2 | Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2017-01-03 | — | — | US | disclosed |
| US-20160200730-A1 | POLYFLUORINATED COMPOUNDS ACTING AS BRUTON TYROSINE KINASE INHIBITORS | Zhejiang DTRM Biopharma Co. Ltd. (CN) | 2016-07-14 | — | — | US | disclosed |
| JP-H02225452-A | PRODUCTION OF BETA-CYANOCARBONYL COMPOUND | RIKAGAKU KENKYUSHO | 1990-09-07 | — | — | JP | disclosed |
| US-3981899-A | FROM TRIAMINOGUANIDINE AND POTASSIUM CYANOFORMATE, HIGH ENERGY FUELS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-09-21 | — | — | US | disclosed |
| US-3981899-A | FROM TRIAMINOGUANIDINE AND POTASSIUM CYANOFORMATE, HIGH ENERGY FUELS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-09-21 | — | — | US | disclosed |