⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854687 | 1.00 | — | — | |
| SCHEMBL23071822 | 1.00 | — | — | |
| SCHEMBL1036149 | 0.83 | DPP4 (0.42) | — | |
| SCHEMBL24140490 | 0.83 | DPP4 (0.42) | — | |
| SCHEMBL12019255 | 0.81 | — | — | |
| SCHEMBL9140084 | 0.80 | USP2 (0.50) | — | |
| SCHEMBL9140089 | 0.80 | USP2 (0.50) | — | |
| SCHEMBL12344727 | 0.80 | — | — | |
| SCHEMBL19198544 | 0.80 | — | — | |
| SCHEMBL19170300 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387608-A1 | ADRENOMEDULLIN-ANALOGUES FOR LONG-TERM STABILIZATION AND THEIR USE | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-08 | — | — | US | disclosed |
| US-11167048-B2 | Dual targeting ligand for cancer diagnosis and treatment | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2021-11-09 | — | — | US | disclosed |
| WO-2020219287-A1 | CAMPTOTHECIN DERIVATIVES | IMMUNOGEN, INC. (US) | 2020-10-29 | — | — | WO | disclosed |
| US-20200255478-A1 | NOVEL COMPOUNDS ACTIVATING THE NRF2 PATHWAY | ALMIRALL SA (ES) | 2020-08-13 | — | — | US | disclosed |
| US-20200188539-A1 | NOVEL DUAL TARGETING LIGAND FOR CANCER DIAGNOSIS AND TREATMENT | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2020-06-18 | — | — | US | disclosed |
| US-9840537-B2 | Selective delivery molecules and methods of use | AVELAS BIOSCIENCES, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| EP-2277884-B1 | ANTHRACYCLINE ANTIBIOTIC DERIVATIVES WITH HIGH ACTIVITY, PREPARATION METHODS AND USES THEREOF | TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) | 2017-08-23 | — | — | EP | disclosed |
| EP-3130608-A1 | (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE | Daiichi Sankyo Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-20160220707-A1 | SELECTIVE DELIVERY MOLECULES AND METHODS OF USE | AVELAS ACQUISITION CORPORATION | 2016-08-04 | — | — | US | disclosed |
| US-9115165-B2 | Tetracyclic anthraquinone antibiotic derivatives with high activity, process for preparing the same and use thereof | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2015-08-25 | — | — | US | disclosed |
| US-20110224161-A1 | TETRACYCLIC ANTHRAQUINONE ANTIBIOTIC DERIVATIVES WITH HIGH ACTIVITY, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2011-09-15 | — | — | US | disclosed |
| EP-2277884-A1 | ANTHRACYCLINE ANTIBIOTIC DERIVATIVES WITH HIGH ACTIVITY, PREPARATION METHODS AND USES THEREOF | Tianjin Hemay Bio-Tech Co., Ltd. (CN) | 2011-01-26 | — | — | EP | disclosed |